Polymer ntxeem tau cov ntaub ntawv yog cov khoom siv polymer nrog ntau qhov pores tsim los ntawm cov pa tawm hauv cov khoom siv polymer.
Cov qauv ntxeem tshwj xeeb no yog qhov zoo heev rau kev siv cov khoom siv suab nrov, kev sib cais thiab adsorption, tshuaj tiv thaiv kev tso tawm, pob txha scaffold thiab lwm yam.
Cov khoom ntxeem tau ib txwm muaj, xws li polypropylene thiab polyurethane, tsis yooj yim rau degraded thiab siv roj av los ua raw khoom, uas yuav ua rau muaj kuab paug ib puag ncig.
Yog li ntawd, tib neeg pib kawm biodegradable qhib-qhov cov ntaub ntawv.
Kev siv cov khoom siv PLA qhib qhov:
PLA cov ntaub ntawv qhib lub qhov tseem muaj qee qhov tsis zoo, uas txwv nws daim ntawv thov hauv thaj chaw qhib-qhov khoom, xws li:
1. Kev ntxhib los mos, tsis muaj zog tensile thiab tsis muaj elasticity ntawm cov khoom perforated.
2. qeeb degradation tus nqi.
Yog tias nyob hauv lub cev ntev ntev raws li cov tshuaj, nws tuaj yeem ua rau mob.
3. Dej ntws.
Tsawg affinity rau cov hlwb, yog ua rau cov pob txha pob txha los yog scaffold hlwb yog ib qho nyuaj rau adhere thiab proliferate.
Txhawm rau txhim kho qhov tsis txaus ntawm PLA qhib-qhov cov ntaub ntawv, kev sib xyaw, txhaws, copolymerization thiab lwm txoj hauv kev tau txais los txhim kho PLA cov ntaub ntawv qhib qhov.
Cov hauv qab no yog ob peb qhov kev hloov kho ntawm PLA:
1.PLA / PCL sib xyaw hloov kho
PCL, lossis polycaprolactone, kuj yog cov khoom siv biodegradable nrog biocompatibility zoo, toughness thiab tensile lub zog.
Kev sib xyaw nrog PLA tuaj yeem txhim kho qhov toughness tensile lub zog ntawm PLA.
Cov kws tshawb nrhiav pom tias cov khoom tuaj yeem tswj tau los ntawm kev tswj hwm qhov piv ntawm PCL rau PLA. Thaum qhov sib piv loj ntawm PLA rau PCL yog 7: 3, lub zog tensile thiab modulus ntawm cov khoom tau siab dua.
Txawm li cas los xij, lub toughness txo nrog qhov nce ntawm pore txoj kab uas hla.
Cov khoom siv PLA / PCL tsis muaj tshuaj lom thiab muaj peev xwm siv rau hauv cov ntaub so ntswg me me.
2.PLA/PBAT muab hloov kho
PBAT yog cov khoom siv degradable, uas muaj qhov degradability ntawm aliphatic polyester thiab toughness ntawm aromatic polyester. Lub brittleness ntawm PLA tuaj yeem txhim kho tom qab sib xyaw nrog PLA.
Cov kev tshawb fawb qhia tau hais tias nrog kev nce ntawm PBAT cov ntsiab lus, qhov porosity ntawm cov khoom qhib lub qhov txo qis (qhov porosity yog qhov siab tshaj plaws thaum PBAT cov ntsiab lus yog 20%), thiab cov pob txha elongation nce.
Qhov zoo siab, txawm hais tias qhov sib ntxiv ntawm PBAT txo qhov tensile lub zog ntawm PLA, lub zog tensile ntawm PLA tseem nce ntxiv thaum nws tau ua tiav rau hauv cov khoom qhib.
3.PLA/PBS sib xyaw hloov kho
PBS yog cov khoom siv biodegradable, uas muaj cov khoom siv zoo, ua haujlwm kub zoo, ua haujlwm yooj yim thiab muaj peev xwm ua tau zoo, thiab ze rau PP thiab ABS cov ntaub ntawv.
Kev sib xyaw PBS nrog PLA tuaj yeem txhim kho qhov brittleness thiab kev ua haujlwm ntawm PLA.
Raws li kev tshawb fawb, thaum qhov sib piv loj ntawm PLA: PBS yog 8: 2, cov txiaj ntsig zoo yog qhov zoo tshaj plaws; Yog tias PBS tau ntxiv ntau dhau, qhov porosity ntawm cov khoom qhib qhov yuav raug txo.
4.PLA / BIOactive iav (BG) hloov kho
Raws li cov khoom siv iav bioactive, BG feem ntau yog tsim los ntawm silicon sodium calcium phosphorus oxide, uas tuaj yeem txhim kho cov khoom siv dag zog thiab bioactivity ntawm PLA.
Nrog rau qhov nce ntawm BG cov ntsiab lus, lub tensile modulus ntawm cov khoom qhib-qhov tau nce, tab sis lub zog tensile thiab elongation ntawm tawg poob.
Thaum cov ntsiab lus BG yog 10%, qhov porosity ntawm cov khoom qhib qhov yog qhov siab tshaj (87.3%).
Thaum BG cov ntsiab lus nce mus txog 20%, lub zog compressive ntawm cov khoom sib xyaw yog qhov siab tshaj plaws.
Tsis tas li ntawd, PLA / BG cov khoom sib xyaw ntxeem tau tuaj yeem tso cov txheej txheem osteoid apatite rau ntawm qhov chaw thiab sab hauv hauv cov kua dej hauv lub cev, uas tuaj yeem tsim cov pob txha. Yog li, PLA / BG muaj peev xwm siv tau rau hauv cov khoom siv pob txha.
Post lub sij hawm: 14-01-22